我院于1989年8月至1990年年5月用多虑平治疗消化性溃疡(PU)76例,疗效较满意。资料和方法一、病例选择选择以上腹痛、饱胀、泛酸等症状就诊并经内镜确诊的76例PU病人。其中30例伴有焦虑、失眠、多疑等精神神经症状。全部病例均无青光眼及严重的肝或心血管疾病。将76例PU病人随机分成两组。两组病人的性别、年龄、病程及溃疡部位和面积的大小基本相似(P>0.05)。二、治疗和观察方法全部病人均在门诊治疗,合并上消化道出血者先止血治疗。多虑平每日75mg,分三次口服;雷尼替丁每日0.3g,睡前顿服。二组治疗前后观察血、尿常规、肝功能及心电 Our hospital from August 1989 to May 1990 with doxepin treatment of peptic ulcer (PU) 76 cases, the effect is more satisfactory. Materials and Methods First, the choice of cases More than the abdominal pain, fullness, pantothenic acid and other symptoms and endoscopic diagnosis of 76 cases of PU patients. 30 cases were accompanied by anxiety, insomnia, paranoid and other neuropsychiatric symptoms. No cases of glaucoma and severe liver or cardiovascular disease in all cases. 76 cases of PU patients were randomly divided into two groups. The two groups of patients’s sex, age, duration and size of the ulcer site and area were similar (P> 0.05). Second, the treatment and observation methods All patients are in outpatient treatment, combined with upper gastrointestinal bleeding hemostasis. Doxepin daily 75mg, three times orally; ranitidine daily 0.3g, Dayton clothing before going to bed. The two groups before and after treatment observed blood, urine, liver function and ECG