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人和动物的严重烧伤除了引起局部和全身的血液动力学、神经内分泌及代谢的改变外,还发现机体血中出现有毒物质。这些毒物可来自烧伤皮肤或内脏,它们在急性烧伤致死上可能起重要作用。 烧伤毒素存在的证据 (1)将烧伤动物的血液、血清或淋巴液注射于正常动物,可产生明显的症状甚至死亡。动物的交叉循环实验也得到类似的结果。(2)从全身循环中除去烧伤部位的循环,提高了烧伤动物的存活率。可能是由于阻
In addition to local and systemic hemodynamics, neuroendocrine and metabolic changes, severe burns in humans and animals have also found toxic substances in the body’s bloodstream. These toxins can come from burns on the skin or offal, which may play an important role in the death of an acute burn. Evidence of the presence of burn toxins (1) Burn animals blood, serum or lymph injection of normal animals, can produce significant symptoms or even death. Animal cross-cycle experiments also yielded similar results. (2) Removing the circulation of the burn site from the systemic circulation improves the survival rate of the burned animal. May be due to resistance