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目的:探讨~(125)Ⅰ放射性粒子在腮腺粘液表皮样癌术后行组织间植入的治疗效果。方法:腮腺粘液表皮样癌病例36例随机分为两组,A组16例腮腺粘液表皮样癌作常规腮腺恶性肿瘤根治手术。B组20例行保留面神经腮腺并肿瘤切除术,尽量将肿瘤切除干净,然后在怀疑有肿瘤残留或安全边界不足处放置125I放射性粒子作为术后辅助治疗。两组病例在性别、年龄、UICC分期、病理分级之间均无显著性差异。术后随访,观察两组病例治疗效果。结果:A组13例有面瘫症状,4例复发;B组无一例出现面瘫症状,无一例复发。结论:腮腺粘液表皮样癌术后辅以放射性粒子植入组织内放疗疗效可靠且方法安全、操作简便,可有效降低腮腺粘液表皮样癌术后并发症和复发率。
Objective: To investigate the therapeutic effect of ~ (125) Ⅰ radioactive particles implantation in the treatment of parotid mucoepidermoid carcinoma after operation. Methods: Thirty-six cases of parotid mucoepidermoid carcinoma were randomly divided into two groups. A group of 16 parotid mucoepidermoid carcinoma was treated by conventional radical treatment of parotid malignant tumor. B group of 20 patients with facial parotid gland preservation and tumor resection, try to remove the tumor clean, and then in the suspected tumor residue or insufficient safety margin 125I radioactive particles placed as postoperative adjuvant therapy. There was no significant difference between the two groups in gender, age, UICC stage and pathological grade. After follow-up, the treatment effect of two groups was observed. Results: There were 13 cases of facial paralysis in group A and 4 cases of recurrence in group A. No case of facial paralysis was found in group B, and none of them recurred. CONCLUSION: Mucous epidermoid carcinoma of the parotid gland is assisted by radioactive seed implantation into the tissue after radiotherapy and is safe, safe and easy to operate. It can effectively reduce postoperative complications and recurrence of parotid mucoepidermoid carcinoma.