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锌作为一种人体必需的金属微量元素,广泛分布于牙菌斑、唾液以及釉质表面,同时,也常被加入口腔清洁类产品中以达到控制菌斑,减少口气,防止牙石形成的目的。尽管有研究显示,锌可以有效地保护牙体硬组织,抑制口腔致龋菌的生长及产酸,在理论上有着良好的抗龋特性,但在实际的临床应用中,锌却没有展现出其在预防及治疗龋病方面的优势。可能是因为锌离子无法大量牢固地粘附于牙体表面,而已附着部分又常会因为各种环境因素的刺激而轻易脱落,从而无法有效发挥防龋效能。本文就锌与牙体硬组织间的相互作用、锌的抗微生物效应及其与龋病发生率的关联等作一综述。
Zinc, as a metal trace element essential to the human body, is widely distributed on the surface of plaque, saliva and enamel. It is also often added to oral cleaning products to control plaque, reduce the tone and prevent the formation of calculus. Although some studies have shown that zinc can effectively protect dental hard tissue, inhibit oral cariogenic bacteria growth and acid production, in theory, has good anti-cariogenic properties, but in practical clinical applications, zinc did not show its In the prevention and treatment of dental caries advantage. It may be because zinc ions can not adhere to the tooth surface in a large amount, and the attached parts often fall off easily due to various environmental factors, thus failing to effectively exert the anticorrosion efficacy. This article reviews the interaction between zinc and dental hard tissue, the antimicrobial effect of zinc and its association with the incidence of dental caries.