环丙沙星是一种新型喹诺酮类衍生物抗菌药物。本文简要介绍其化学结构、吸收、代谢、分布和排泄的临床药物动力学过程及体外实验研究,认为它在临床应用中具有广谱抗菌作用,特别是对耐其它抗生素的绿脓杆菌等革兰阴性杆菌有较好的效果,具有毒副作用小,可口服等优点。 Ciprofloxacin is a novel quinolone derivative antimicrobial. In this paper, we briefly introduce the clinical pharmacokinetics of its chemical structure, absorption, metabolism, distribution and excretion and its in vitro experimental study. It is considered that it has a broad spectrum of antibacterial activity in clinical application, especially for Gram-negative bacteria such as Pseudomonas aeruginosa which are resistant to other antibiotics Negative bacilli has a good effect, with toxic side effects, can be oral and other advantages.