【摘 要】
:
A new ureido-substituted amino acid,conopsamide A(1),has been isolated from an ethanolic extract of the tubers of Gymnadenia conopsea.Its structure was elucidat
【机 构】
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College of Pharmaceutical Sciences, Qinghai University for Nationalities,State Key Laboratory of Bio
【出 处】
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Chinese Chemical Letters
论文部分内容阅读
A new ureido-substituted amino acid,conopsamide A(1),has been isolated from an ethanolic extract of the tubers of Gymnadenia conopsea.Its structure was elucidated by extensive spectroscopic analysis,and the absolute configuration was assigned by Marfey’s method.The new compound was evaluated for in vitro assay for HDACl(Histone Deacetylase 1) inhibitory activity.
A new ureido-substituted amino acid, conopsamide A (1), has been isolated from an ethanolic extract of the tubers of Gymnadenia conopsea. Its structure was elucidated by extensive spectroscopic analysis, and the absolute configuration was assigned by Marfey’s method. The new compound was evaluated for in vitro assay for HDAC1 (Histone Deacetylase 1) inhibitory activity.
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