通过对动物的急性致毒试验,证实增效磷属于低毒性药剂的结果在前文中已有报道。为了阐明增效致磷在较长期多次重复染毒情况下,对动物致毒作用的特点,进一步研究和观察动物的中毒症状,以及判断该药是否存在有潜在的遗传性危害,以评价该药剂的安全性和应用价值。我们进行了亚急性毒性、致畸、致突变等系列的试验研究。 Through the acute toxicity test to animals, the result of confirming that the synergistic phosphorus belongs to the low toxicity medicament has been reported in the foregoing. In order to clarify the characteristics of toxicogenic effects of synergistic-induced phosphorus in long-term repeated multiple exposures to animals, further study and observation on the symptoms of animal poisoning, and the potential hereditary hazards of the drug, Pharmacy safety and application value. We conducted sub-acute toxicity, teratogenic, mutagenic and other series of experimental studies.