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低剂量Ｓ１８６对大鼠和犬体内的锶具有促排效果。大鼠静注８５＋８９Ｓｒ后，肌注不同剂量Ｓ１８６（２０，５０，１００，２００ｍｇ／ｋｇ），观察２ｄ内尿中８５＋８９Ｓｒ排出量和整体、骨骼中蓄积量。当Ｓ１８６剂量为５０ｍｇ／ｋｇ时，大鼠尿中８５＋８９Ｓｒ排出量比对照组增加８５％，整体和骨骼中蓄积量显著下降（Ｐ＜０．０５）。Ｓ１８６伍用中－６（鸡内金），促排效果进一步提高。犬口服氯化锶５０ｍｇ，用药组于０．５ｈ后肌注Ｓ１８６０．５ｇ，２４ｈ后再次肌注０．５ｇ，分别收集各犬２４ｈ尿，共４ｄ，采用ＰＥ－３０３０原子吸收分光光度仪测定尿锶排出量，可见用药犬尿锶排出量比对照犬增加。
Low-dose S186 has a promoting effect on fleas in rats and dogs. After intravenous injection of 85+89Sr to rats, intramuscular injection of different doses of S186 (20, 50, 100, 200 mg/kg) was performed to observe the discharge of 85+89Sr in the urine within 2 days and the total and bone accumulation in the urine. When the dose of S186 was 50mg/kg, the discharge of 85+89Sr in the urine of rats was increased by 85% compared with the control group, and the total volume and the amount of bone accumulation decreased significantly (P<0.05). S186 Wu used medium-6 (chicken inner gold) to further enhance the row effect. The dogs were given oral guanidinium chloride (50mg). The drug group was intramuscularly injected with S1860.5g 0.5 hours later. After 24 hours, 0.5g was injected intramuscularly again. Each dog was allowed to urine for 24 hours for 4 days. The urine was measured by PE-3030 atomic absorption spectrophotometer. The amount of sputum output showed that the urine output of the drug dog was increased compared with the control dog.