砷化氢(AsH_3)为无色、无刺激性的气体,接触浓度3～10ppm的空气数小时可发生症状。砷或金属的砷化物在水中与新生态氢反应释出AsH_3。大多数中毒病例是在用酸处理含砷的天然金属或矿石时产生AsH_3所引起的。相当多AsH_3中毒发生于熔化和提纯金属时,但有时因镀锌、热焊接、蚀刻及制铅板也可产生致死剂量的AsH_3。近来报导污水中的真菌可利用水中的砷产生AsH_3。使用多种化学杀虫剂的林业工人也有可能遇到这种气体。最近对煤等矿物燃料作为能源重感兴趣,AsH_3中毒有上升趋势。这些燃料含相当量砷,在高温、压力及蒸气的作用下产生AsH_3。一、临床表现 Arsine (AsH 3) is a colorless, non-irritating gas that can come into contact with air at concentrations of 3 to 10 ppm for hours. Arsenic or metal arsenide reacts with neo-hydrogen in water to release AsH 3. Most cases of poisoning are caused by the production of AsH 3 when treated with acid for arsenic-containing natural metals or ores. Quite a lot of AsH 3 poisoning occurs when melting and purifying metals, but sometimes lethal doses of AsH 3 can also be produced by galvanizing, heat welding, etching, and lead-free board. It has recently been reported that fungi in wastewater can utilize arsenic in water to produce AsH 3. Forestry workers using multiple chemical pesticides are also likely to encounter this gas. Recent interest in fossil fuels such as coal as an energy source has shown an upward trend in AsH 3 poisoning. These fuels contain a considerable amount of arsenic and produce AsH 3 at high temperatures, pressures and vapors. First, the clinical manifestations