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患者,女,26岁,朝鲜族。自1987年4月起,颜面反复出现红斑及瘙痒性丘疹,经各种治疗,皮损仍复发。患病部位活检可见血管周围单核细胞浸润,伴少许嗜伊红细胞,表皮无明显改变。用欧洲标准斑试系列进行斑贴试验,于斑试后48及96小时观察结果,发现对新霉素呈弱阳性反应(+);镍呈强阳性反应(++)。患者3年前搬到现在的住处后,每日用地下水洗脸3次,每次用水2～3升,时间长短不一,自从用自来水代替地下水后,脸上很少出现皮疹,故作者一周内收集了7次患者使用的地下水,同时收集别处地下
Patient, female, 26 years old, Korean. Since April 1987, repeated facial redness and pruritus pimples, after various treatment, skin lesions are still relapse. Diseased biopsies showed perivascular mononuclear cell infiltration, with a small number of eosinophils, no significant change in the epidermis. Plaque test was performed with the European standard plaque test series. The results were observed 48 and 96 hours after the plaque test and found to be weakly positive (+) for neomycin and strong positive for nickel (++). Patient moved to the present residence three years ago, washed 3 times a day with groundwater, each 2-3 liters of water, the length of time since the replacement of groundwater with tap water, the face rarely rash, so the author within a week The groundwater collected by the patient for 7 times was collected while collecting underground elsewhere