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目的探讨经颅多普勒超声微栓子信号在阻塞性睡眠呼吸暂停低通气综合征(OSAHS)合并脑梗死患者中的表现。方法采用多通道经颅多普勒超声进行42例健康志愿者双侧大脑中动脉的监测,40例单纯OSAHS、42单纯脑梗死以及39例OSAHS合并脑梗死患者经颅多普勒超声微栓子信号(MES)检测。结果脑梗死组、OSAHS组、OSAHS+脑梗死组MES明显高于正常对照组(P<0.01);OSAHS+脑梗死组MES高于脑梗死组(P<0.01),也高于OSAHS组(P<0.01)。结论 OSAHS患者MES增高可能是导致脑梗死发生的原因之一。对OSAHS患者的MES进行干预可作为OSAHS的辅助治疗方法,对预防脑梗死的发生及发展也有一定的临床意义。
Objective To investigate the clinical manifestations of transcranial Doppler ultrasonography in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) complicated with cerebral infarction. Methods The monitoring of bilateral middle cerebral arteries in 42 healthy volunteers was performed by multichannel transcranial Doppler sonography. Twenty-four patients with simple OSAHS and 42 simple cerebral infarction and 39 patients with OSAHS complicated with cerebral infarction received transcranial Doppler ultrasonography Signal (MES) detection. Results The MES of cerebral infarction group, OSAHS group and OSAHS + cerebral infarction group was significantly higher than that of normal control group (P <0.01). The MES of OSAHS + cerebral infarction group was higher than that of cerebral infarction group (P <0.01) ). Conclusion The increase of MES in patients with OSAHS may be one of the causes of cerebral infarction. The intervention of OSAHS patients with MES can be used as an adjuvant treatment of OSAHS, to prevent the occurrence and development of cerebral infarction also has some clinical significance.