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目的:评价CO2激光包皮环切术联合氦氖激光治疗包皮过长并尖锐湿疣的临床疗效。方法:将包皮过长并尖锐湿疣的患者120例,随机分为治疗组60例,对照组60例。治疗组行CO2激光包皮环切术,对照组行CO2激光术祛除疣体,两组均联合氦氖激光治疗。两组治疗后,均随访6个月,对两组疗效及复发率进行对比。结果:治疗组痊愈55例,痊愈率为91.67%;对照组痊愈44例,痊愈率为73.33%,两组疗效比较,差异显著(χ2=6.98,P=0.008P<0.05);随访6个月,治疗组55例,复发5例,复发率为9.1%,对照组44例,复发14例,复发率为31.8%,两组复发率比较,差异显著(χ2=8.14P=0.004P<0.05)。结论:CO2激光包皮环切术联合氦氖激光治疗包皮过长并尖锐湿疣,临床疗效显著,复发率低,值得临床推广。
Objective: To evaluate the clinical effect of CO2 laser circumcision combined with He-Ne laser in the treatment of long foreskin and condyloma acuminatum. Methods: 120 cases of prepuce and condyloma acuminatum were randomly divided into treatment group (60 cases) and control group (60 cases). CO2 laser circumcision was performed in the treatment group and CO2 laser was used in the control group to eliminate the wart. Both groups were treated with He-Ne laser. After two groups of treatment, were followed up for 6 months, the two groups were compared efficacy and recurrence rate. Results: In the treatment group, 55 cases were cured and the cure rate was 91.67%. In the control group, 44 cases were cured and the cure rate was 73.33%. There was significant difference between the two groups (χ2 = 6.98, P = 0.008P <0.05) , 55 cases in the treatment group, 5 cases relapsed, the recurrence rate was 9.1%, 44 cases in the control group and 14 cases relapsed, the recurrence rate was 31.8%. There was significant difference between the two groups (χ2 = 8.14P = 0.004P <0.05) . Conclusion: CO2 laser circumcision combined with He-Ne laser treatment of prepuce and genital warts, clinical significant effect, low recurrence rate, worthy of clinical promotion.