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目的研究冠心病患者血清瘦素(Leptin)水平的变化,探讨其与冠心病严重程度的关系。方法收集120例冠心病患者根据病情分为稳定性心绞痛组(36例)、急性冠脉综合征组(62例)及ST段抬高型心肌梗死组(22例),并收集50例排除冠心病成人作为对照组,比较各组冠心病患者及对照组血清瘦素水平。结果与正常对照组比较,冠心病患者血清瘦素水平显著升高,且冠心病患者各组间随着冠心病严重程度增加,血清瘦素水平也逐渐升高。结论血清瘦素水平检测对冠心病严重程度具有较好的预测价值。
Objective To study the changes of serum Leptin level in patients with coronary heart disease and to explore its relationship with the severity of coronary heart disease. Methods A total of 120 patients with coronary heart disease were divided into stable angina group (36 cases), acute coronary syndrome group (62 cases) and ST-segment elevation myocardial infarction group (22 cases) Adults with heart disease as control group, serum leptin levels in patients with coronary heart disease and control group were compared. Results Compared with the normal control group, the level of serum leptin in patients with coronary heart disease was significantly higher, and the severity of coronary heart disease increased with the severity of coronary heart disease. The serum leptin levels also gradually increased. Conclusion The serum leptin level has a good predictive value for the severity of coronary heart disease.