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中医在治疗类风湿关节炎(RA)上有一定的优势,且辨证论治在RA的临床诊治中发挥着重要的作用.近年来,关于RA中医证候的研究颇多,包括基本的临床经验辨证分型,以及影响证型的年龄、性别、病程、地域等方面的因素归类;与中医证候相关联的病理生理学、免疫学、分子生物学等指征之间的规律;辨病与辨证相结合治疗RA能提高整体疗效,并从现代药理学机制出发,沟通“方证”在分子生物网络之间的联系.这些研究丰富了证候信息的内容,有利于从宏观与微观角度把握证候的本质,但RA证候规范化的研究仍存在诸多不足,有待不断补充和完善.“,”Traditional Chinese medicine shows certain advantages in the treatment of rheumatoid arthritis (RA),and the syndrome differentiation and treatment play an important role in the clinical diagnosis and treatment of RA.In recent years,there are a lot of research on Chinese medical syndrome of RA,including the basic syndrome differentiation of clinical experience,classification of factors that influencing syndrome type (age,sex,duration,region and so on),relationship with indications associated with Chinese medical syndrome such as pathological physiology,immunology and molecular biology,combination of disease differentiation and syndrome differentiation in the treatment of RA which improve the overall efficacy and connect the prescription and syndrome in molecular biological networks based on modem pharmacological mechanism.These studies enrich the contents of syndrome information,which help to grasp the syndrome essence from the macro and micro perspectives.However,there are still many deficiencies in the study of RA syndrome standardization,which need to be constantly supplemented and improved.