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目的探索脑心通胶囊联合奥扎格雷钠治疗糖尿病合并脑梗死患者的临床疗效。方法 60例糖尿病合并脑梗死患者,随机分为观察组和对照组,每组30例。对照组采用常规治疗,观察组采用脑心通胶囊联合奥扎格雷钠治疗。比较两组临床疗效。结果治疗后,观察组患者的纤维蛋白原、全血高切粘度、血浆粘度均显著优于对照组,差异有统计学意义(P<0.05);观察组患者空腹血糖平均值(7.23±1.14)mmol/L,餐后2 h血糖均值(10.44±1.21)mmol/L,对照组患者空腹血糖平均值(9.58±2.96)mmol/L,餐后2 h血糖均值(12.97±2.20)mmol/L。观察组患者的空腹血糖平均值和餐后2 h血糖均值低于对照组,差异具有统计学意义(P<0.05)。结论脑心通胶囊联合奥扎格雷钠治疗糖尿病合并脑梗死患者效果显著,值得临床推广。
Objective To explore the clinical efficacy of Naoxintong capsule combined with ozagrel sodium in the treatment of diabetic patients with cerebral infarction. Methods Sixty diabetic patients with cerebral infarction were randomly divided into observation group and control group, 30 cases in each group. Control group with conventional treatment, observation group using Naoxintong capsules combined with ozagrel sodium treatment. The clinical efficacy of the two groups were compared. Results After treatment, fibrinogen, whole blood high shear viscosity and plasma viscosity in observation group were significantly better than those in control group (P <0.05); mean fasting blood glucose (FBG) in observation group was (7.23 ± 1.14) The average fasting blood glucose (9.58 ± 2.96) mmol / L and mean postprandial blood glucose (12.97 ± 2.20) mmol / L were observed in the control group at 2 h after meal. The mean fasting blood glucose and mean postprandial blood glucose at 2 hours in observation group were lower than those in control group (P <0.05). Conclusion Naoxintong capsules combined with ozagrel sodium in patients with diabetes mellitus complicated by cerebral infarction has a significant effect and is worthy of clinical promotion.