作者报告2例坏死性涎腺组织化生(necrotizing Sialometaplasia),结合文献综合如下: 文献中已报告的坏死性涎腺组织化生,男性(10例)略多于女性(5例),无种族差异,年龄23—66岁,73%。40岁或超过40岁。发病前和发病时无全身症状,大多仅主诉腭部溃疡或伴轻微疼痛。病变多见于硬腭,少数见于软腭。溃疡多为园形,偶呈线状,直径1—3厘米,边缘垂直。病变较深,周围可有狭窄的红晕。一般为单个,发生在腭中线或在一侧,少数有2个溃疡,分开于硬腭两侧。组织学特点有二:第一是小涎腺组织的腺泡细胞坏死,第二是有的腺泡被增生的鳞 The authors report two cases of necrotizing Sialometaplasia. The combined literature is as follows: The necrotic salivary tissue metaplasia has been reported in the literature. There are slightly more males (10 cases) than females (5 cases) and no race. Difference, age 23-66, 73%. 40 years old or over 40 years old. There were no systemic symptoms before and at the time of onset, and most of them only complained of ankle ulcers or mild pain. Lesions are more common in hard palate than in soft palate. Most of the ulcers are round-shaped, evenly linear, with a diameter of 1-3 cm and vertical edges. The lesion is deep and there is a narrow blush around it. Usually single, occurs in the midline or on one side of the skull, a few have two ulcers, separated on both sides of the hard palate. There are two histological features: the first is the acinar cell necrosis of the small salivary gland tissue, and the second is the scale of some acini is hyperplasia