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为了解小剂量灭活卡介苗对慢性阻塞性肺病（简称慢阻肺）肺气虚患者细胞免疫功能的影响，对小剂量灭活卡介苗治疗（０．５年）前后细胞免疫功能进行了观察。结果表明，慢阻肺肺气虚患者５４例外周血Ｔ淋巴细胞亚群（ＣＤ３、ＣＤ４、ＣＤ８、ＣＤ４／ＣＤ８）及淋巴细胞转化率均明显低于健康人组（Ｐ＜０．０１）；经小剂量灭活卡介苗治疗０．５年后，其Ｔ淋巴细胞亚群及淋巴细胞转化率明显改善（Ｐ＜０．０１或Ｐ＜０．０５）。表明小剂量灭活卡介苗能调节已被减弱的细胞免疫功能。
In order to understand the effect of low-dose BCG inactivation on cellular immune function in chronic obstructive pulmonary disease (COPD) patients with pulmonary qi deficiency, cellular immune function was observed before and after low-dose BCG inactivation (0.5 years). The results showed that the levels of T lymphocyte subsets (CD3, CD4, CD8, CD4 / CD8) and lymphocyte transformation rate in peripheral blood of 54 patients with chronic obstructive pulmonary disease were significantly lower than those in healthy people (P <0.01) Small-dose inactivated BCG treatment of 0.5 years later, the T lymphocyte subsets and lymphocyte transformation rate was significantly improved (P <0.01 or P <0.05). This shows that low doses of BCG inactivated can attenuate cellular immunity that has been attenuated.