Dear Editor,Clustered regularly interspaced short palindromic repeats (CRISPR) system is part of the adaptive immunity of bacteria and archaea that defends them against phage infection (Barrangou and Doudna,2016).Variant CRISPR systems have been identified and hamessed for a wide range of applications in various organisms,exemplified by gene editing with the CRISPR/Cas9 system from Streptococcus pyogenes (Barrangou and Doudna,2016).