论文部分内容阅读
以往关于干扰素对慢性肝炎作用的研究表明,慢性乙型肝炎病毒感染时,外周血白细胞产生干扰素减少,该发现提示干扰素系统可能参与慢性乙型肝炎的发病机制。甲型肝炎不呈慢性,且为良性过程,与乙型肝炎不同。干扰素是否有助于甲型肝炎患者体内病毒的清除,目前尚不清楚。新近报道在一些甲型肝炎患者和感染甲型肝炎病毒的黑猩猩血清中可测到干扰素,作者对较多急性甲型肝炎患者血清中出现干扰素的频率进行了研究。
Previous studies on the effect of interferon on chronic hepatitis have shown that interferon decreases in peripheral leukocytes during chronic hepatitis B infection, suggesting that interferon may be involved in the pathogenesis of chronic hepatitis B. Hepatitis A is not chronic, and is a benign process, different from hepatitis B. It is not clear whether interferon can help to eradicate the virus in hepatitis A patients. Recently, interferon was detected in sera from some Hepatitis A patients and chimpanzees infected with Hepatitis A, and the authors investigated the presence of interferon in the serum of more patients with acute hepatitis A.