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目的探讨Ⅰ类切口手术围手术期预防性应用抗菌药物的使用情况,并分析合理用药的临床效果。方法 204例Ⅰ类切口围手术期患者,随机分为观察组和对照组,各102例。观察组患者行抗菌药物干预,对照组患者未行抗菌药物干预,观察分析两组患者预防性实施抗菌药物的使用次数、种类以及合理用药情况。结果观察组切口感染率为2%,对照组切口感染率为4%,比较差异无统计学意义(P>0.05);两组患者在药物合理利用方面比较差异有统计学意义(P<0.05)。结论医院必须加强Ⅰ类切口手术围手术期预防性应用抗菌药物的管理,严格遵守《抗菌药物临床应用指导原则》,以促进规范医院I类切口手术预防性应用抗菌药物的使用。
Objective To investigate the perioperative prophylactic use of antibacterials in class Ⅰ incision and to analyze the clinical effects of rational use of antibacterials. Methods A total of 204 patients with type I perioperative incision were randomly divided into observation group and control group, with 102 cases in each group. Patients in the observation group were treated with antibacterial drugs. Patients in the control group were not given antimicrobial interventions. The number of antimicrobial agents used, the types of antimicrobial agents used and the rational use of drugs were observed and analyzed in both groups. Results The incision infection rate was 2% in the observation group and 4% in the control group. There was no significant difference between the two groups (P> 0.05). There was significant difference between the two groups in the rational use of drugs (P <0.05) . Conclusion The hospital should strengthen the perioperative management of antimicrobial agents for perioperative management of type Ⅰ incision and strictly abide by the Guiding Principles of Clinical Application of Antibacterial Drugs to promote the use of preventive antibacterials in Class I incisional surgery in hospitals.