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110例难治性肾病中,单纯性肾病77例(70％),肾炎性肾病33例(30％)。病理类型:MsPGN 44.5％,IgMN 20.9％,IgAN 11.8％,C_(lq)肾病0.9％,以系膜增生改变者占大多数,共78.1％。MCD 6.4％,ML 4.5％,EnP 2.7％,CrGN 2.7％,FsGS、MPGN、FP各1.8％。病理类型轻的MCD,ML仅见于单纯性肾病,轻度MsPGN,IgMN以单纯性肾病多见。病理类型重的MPGN,CrGN,FP只见于肾炎性肾病。疗效:单纯性肾病完全缓解94.8％,肾炎性肾病完全缓解45.5％,二者疗效相差非常显著(P<0.01)。EnP、IgMN、MCD、ML疗效较好,MPGN、CrGN疗效较差。
Of 110 refractory nephrotic diseases, 77 (70%) had simple nephrotic disease and 33 (30%) had nephritis nephropathy. Pathological types: MsPGN 44.5%, IgMN 20.9%, IgAN 11.8%, C_ (lq) nephropathy 0.9%, the majority of mesangial proliferation accounted for a total of 78.1%. MCD 6.4%, ML 4.5%, EnP 2.7%, CrGN 2.7%, FsGS, MPGN, FP 1.8% each. Pathological types of mild MCD, ML only seen in simple nephropathy, mild MsPGN, IgMN more common in simple nephrotic. Pathological types of heavy MPGN, CrGN, FP found only in nephritis kidney disease. Efficacy: simple nephrotic complete remission 94.8%, nephritis nephropathy completely relieved 45.5%, the difference between the two efficacy is very significant (P <0.01). EnP, IgMN, MCD, ML better effect, MPGN, CrGN less effective.