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原发于骨的淋巴瘤少见,约占原发骨肿瘤的5%,多为非何杰金淋巴瘤,通常是弥漫的组织细胞淋巴瘤,在所有原发骨恶性病变中预后最好。在何杰金和非何杰金淋巴瘤中常见继发浸润,在整个病程期间,16%的病例有骨浸润,儿童骨浸润发病率更高,近25%。作者报道25%以上何杰金和20%弥漫性的非何杰金淋巴瘤病例有骨受累,最好发于脊柱、骨盆和颅骨。在非何杰金氏病中,弥漫的溶骨性破坏是最常见的放射学表现,骨皮质破坏常伴邻近肌肉和软组织受累,原发非何杰金淋巴瘤最好发于下肢,在何杰金氏病中原发骨受累极罕见,而血原性和自邻近结节直接播散到骨的转移性病变常见,尤以内乳淋巴结扩散到胸骨常见,病变可为硬
Primary lymphomas rare in bone, accounting for about 5% of primary bone tumors, mostly non-Hodgkin’s lymphoma, usually diffuse histiocytic lymphoma, the best prognosis in all primary bone malignant lesions. Secondary infiltrates are common in Hodgkin and non-Hodgkin’s lymphomas. During the entire course of the disease, bone infiltration occurred in 16% of cases, and the incidence of bone infiltration in children was higher, nearly 25%. The authors reported that more than 25% of Hodgkin’s and 20% of diffuse non-Hodgkin’s lymphoma cases had bone involvement, preferably in the spine, pelvis, and skull. In non-Hodgkin’s disease, diffuse osteolytic destruction is the most common radiological manifestation, cortical bone destruction is often associated with adjacent muscle and soft tissue involvement, primary non-Hodgkin’s lymphoma is best in the lower extremity, where The primary bone involvement in JK disease is extremely rare, and the hematogenous and metastatic lesions that spread directly from the adjacent nodules to the bone are common, especially the common breast lymph nodes spread to the sternum. The lesions can be hard.