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披麻草为百合科植物大理藜芦Veratrumtaliense Loes.f.的全草,大多以根作为药用并已进行了药理研究。但叶鞘与根镇痛作用和毒性的研究未见报道。本文就这方面的研究报告如下: 材料药物:披麻草根流浸膏,每克相当于2.36克原生药。披麻草叶鞘流浸膏,每克相当于2.575克原生药。动物:昆明远交系小白鼠由本所动物房供给。方法与结果一、披麻草根,叶鞘对小白鼠半数致死量的测定方法:取体重18~22克雌雄各半小白鼠100只,每组10只,根、叶鞘各五组,不同剂
Phanthera pratensis is the whole plant of the Liliaceae plant Dali Veratrumtaliense Loes.f., and most of the roots are used as medicinal plants and pharmacological studies have been conducted. However, studies on the analgesic effect and toxicity of leaf sheath and root have not been reported. In this article, the research report in this regard is as follows: Material Drugs: The root extract of the shemp seed is equivalent to 2.36 grams of crude drug per gram. A shemp leaf sheath extract, equivalent to 2.575 grams of crude drug per gram. Animals: Kunming outbred mice were supplied by the animal house. Methods and Results I. Method for determination of median lethal dose of shemp root and leaf sheath on mice: 100 male and half female rats weighing 18-22 g, 10 mice in each group, 5 root and leaf sheaths, and different agents