啮齿类动物和正常人淋巴样细胞,不需任何抗原预先致敏,或抗体、补体的参与,能够在体外破坏或溶解各种靶细胞(包括肿瘤细胞、病毒感染的细胞和某些正常细胞)。这种现象被称为天然杀伤,参与这种细胞毒性的效应细胞称为天然杀伤细胞(NK细胞)。有人认为NK细胞在宿主发生肿瘤的免疫监管机制中可能起着第一防线的作用。最近 Rodents and normal human lymphoid cells do not require any antigen pre-sensitization, or the participation of antibodies and complements, can destroy or dissolve various target cells (including tumor cells, virus-infected cells, and certain normal cells) in vitro. . This phenomenon is called natural killing and the effector cells involved in this cytotoxicity are called natural killer cells (NK cells). Some people think that NK cells may play a first line of defense in the immune regulatory mechanism of host tumors. recent