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目的:观察雌激素联合甲硝唑治疗萎缩性阴道炎的临床效果。方法:以我院2013年3月~2015年3月收治的200例萎缩性阴道炎患者为研究对象,随机分为观察组和对照组,每组100例,其中对照组以甲硝唑栓剂为治疗药物,观察组在予以雌激素联合甲硝唑栓剂的治疗,治疗一段时间后,观察两组患者的临床治疗效果,其他各项指标的变化情况以及是否产生不良反应。结果:经过不同的治疗,观察组患者的临床治疗效果明显大于对照组,且差异具有统计学意义(P<0.05),观察组患者的子宫内膜厚度、表层细胞百分比、阴道清洁度和阴道p H值的改善程度均明显高于对照组,且差异具有统计学意义(P<0.05)。结论:雌激素联合甲硝唑治疗萎缩性阴道炎的临床效果显著,能够有效的增加子宫内膜厚度、表层细胞百分比,提高阴道清洁度,改善阴道p H值,值得在临床治疗中应用和推广。
Objective: To observe the clinical effect of estrogen combined with metronidazole in the treatment of atrophic vaginitis. Methods: 200 patients with atrophic vaginitis treated in our hospital from March 2013 to March 2015 were randomly divided into observation group and control group, with 100 cases in each group. Metronidazole suppository The treatment group was treated with estrogen combined with metronidazole suppository. After a period of treatment, the clinical effects of the two groups of patients, the changes of other indexes and the occurrence of adverse reactions were observed. Results: After different treatments, the clinical effect of the observation group was significantly greater than that of the control group, and the difference was statistically significant (P <0.05). The endometrial thickness, the percentage of superficial cells, the vaginal cleanliness and vaginal p The improvement of H value was significantly higher than that of the control group, and the difference was statistically significant (P <0.05). Conclusion: The clinical effect of estrogen plus metronidazole in the treatment of atrophic vaginitis is significant, which can effectively increase the thickness of the endometrium, the percentage of the surface cells, improve the vaginal cleanliness and improve the vaginal p H value, which is worthy of application and promotion in clinical treatment .