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目的:探讨早期输尿管癌保留肾脏手术的可行性及疗效。方法:回顾性分析2004年6月～2010年8月15例早期输尿管癌保肾手术患者的临床资料,9例行输尿管节段切除端端吻合术;6例行输尿管末端及膀胱袖口状切除,输尿管膀胱再植术。术后均行膀胱灌注化疗。结果:本组15例患者术后病理均为移行细胞癌。14例获得随访6个月～5年,所有患者同侧输尿管及肾盂均未见复发,2例术后分别于9个月及3年出现膀胱移行细胞癌,术后膀胱癌发生率为14.3%(2/14)。结论:输尿管癌为少见尿路上皮肿瘤,保肾手术有复发的风险。但对早期、低级别输尿管癌,保肾手术效果良好。
Objective: To investigate the feasibility and efficacy of preserving renal surgery in early ureteral cancer. Methods: The clinical data of 15 patients with ureteral carcinoma with renal preservation surgery from June 2004 to August 2010 were retrospectively analyzed. 9 patients underwent ureteral segmentectomy and end-to-end anastomosis. 6 patients underwent ureter and bladder cuff resection, Ureteral bladder replantation. Postoperative bladder perfusion chemotherapy. Results: The 15 patients in this group were pathologically transitional cell carcinoma. Fourteen patients were followed up for 6 months to 5 years. No recurrence of ipsilateral ureter and renal pelvis was observed in all patients. Two cases had bladder transitional cell carcinoma at 9 months and 3 years respectively. The incidence of postoperative bladder cancer was 14.3% (2/14). Conclusions: Ureteral cancer is a rare urothelial cancer and there is a risk of recurrence of kidney-conserving surgery. However, early, low-grade ureteral cancer, kidney surgery good effect.