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最近,血液学的研究取得了广泛而飞速的进步,在有限的纸上是无法概括这一切的。本文主要叙述造血调节因子、白血病、凝固纤溶系统和用遗传工程法进行治疗等问题。一、造血调节因子对血液学基础—造血的研究,随着造血因子的纯化、造血相关因子和受体基因克隆培养技术等的发展而取得飞速进步。Jacobs、Miyake 等成功地研制出历来被认为是典型的成红细胞调节因子—人类促红细胞生成素(EP)的 CDNA 模式,并确立了其完整的一级结构。他们认为,EP 是由166个氨基酸组成,分子量约为18,000。
Recently, extensive and rapid advances have been made in the study of hematology, which can not be summarized on limited paper. This article describes the hematopoietic factors, leukemia, coagulation and fibrinolysis system and the use of genetic engineering for treatment and other issues. First, the hematopoietic regulatory factors on hematology - hematopoietic research, with the purification of hematopoietic factors, hematopoietic related factors and receptor gene cloning and culture of technology and made rapid progress. Jacobs, Miyake et al. Successfully developed the CDNA pattern of human erythropoietin (EP), a typical erythroid regulation factor, and established its complete primary structure. They think that EP is composed of 166 amino acids and has a molecular weight of about 18,000.