IgA肾病是指肾小球系膜区有广泛、显著的IgA沉着的肾小球疾患,故为一免疫病理诊断。1968年首先由Berger和Hinglais所报导,故又称Berger病。从免疫病理的角度考虑,系膜IgA沉着可见于多种全身性疾患(如过敏性紫癜、系统性红斑狼疮、酒精性肝硬变、门体分流、疱疹样皮炎、蕈样肉芽肿、能分泌白蛋的癌肿、麻风、肺含铁血黄素沉着症、肝炎、家族性血小板减少性紫癜、强直性脊柱炎、周期性白细胞降低等症),通常所说的IgA肾病是指特发性者,即在排除上述全身疾患后、原因不明的 IgA nephropathy refers to the glomerular mesangial area has a wide range of significant glomerular IgA disorders, it is a diagnosis of immunopathology. First reported by Berger and Hinglais in 1968, it is also known as Berger’s disease. From an immunopathological point of view, mesangial IgA deposition can be seen in a variety of systemic conditions (eg, allergic purpura, systemic lupus erythematosus, alcoholic cirrhosis, portal shunt, dermatitis herpetiformis, mycosis fungoides, Leprosy, pulmonary hemosiderosis, hepatitis, familial thrombocytopenic purpura, ankylosing spondylitis, periodic leukopenia embolism), commonly referred to as IgA nephropathy refers to idiopathic , That is to exclude the above systemic disorders, the reason is unknown