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目的 研究以术前前列腺活检资料来推断前列腺癌体积及病理的价值。方法 以 3 3例因前列腺癌而行根治术的患者作为研究对象 ,将术前PSA、PSAD及前列腺 8点活检的结果与前列腺癌体积及病理进行相关分析研究。结果 (1)前列腺癌体积与术前PSA、PSAD及前列腺活检的结果呈显著正相关 ,而与年龄、术前前列腺体积以及摘除标本的体积无明显相关关系 ;(2 )前列腺活检中阳性点数联合PSA与前列腺癌体积的回归模型预测前列腺癌体积最好 ;(3 )前列腺活检中阳性点数≤ 3点组的癌体积及精囊浸润率低于阳性点数≥ 4点组 ,两者有显著性差异。结论 前列腺 8点活检中阳性点数是预测前列腺癌体积及病理的一个重要参考指标 ,尤其是联合检测PSA ,更增加其预测前列腺癌体积的准确性
Objective To study the value of preoperative prostate biopsy to infer the volume and pathology of prostate cancer. Methods A total of 33 patients undergoing radical resection of prostate cancer were included in this study. The results of preoperative PSA, PSAD and 8-point biopsy of prostate were analyzed in correlation with the volume and pathology of prostate cancer. Results (1) There was a significant positive correlation between the volume of prostate cancer and the results of preoperative PSA, PSAD and prostate biopsy, but not with the age, preoperative prostate volume and volume of extirpated specimens. (2) The regression model between PSA and prostate cancer volume predicted the best prostate cancer volume. (3) The cancer volume and the seminal vesicle infiltration rate of positive points ≤ 3 points in prostate biopsy were lower than the positive points ≥ 4 points, both of which were significantly different. Conclusions The positive points in the 8-point biopsy of prostate are an important reference index for predicting the size and pathology of prostate cancer. In particular, the combined detection of PSA increases the accuracy of predicting the volume of prostate cancer