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调查溃疡性结肠炎患者的营养与免疫状况,评价全面的主观评价(SGA)方法对该病的应用价值。检测30例溃疡性结肠炎患者和30例健康人的血浆白、球蛋白,转铁蛋白,免疫球蛋白,可溶性白细胞介素-2受体(sIL-2R),C反应蛋白(CRP)及B因子水平,同时用SGA方法对患者作营养评价。结果显示溃疡性结肠炎患者血浆转铁IgA、IgM明显低于健康人。SGA评价显示20例为中度营养不良,2例为重度营养不良,8例为营养正常。结论:溃疡性结肠炎患者中多数存在营养不良和免疫异常,用SGA评估营养状况结果与其内脏蛋白质及细胞免疫指标的改变一致。
To investigate the nutritional and immune status of patients with ulcerative colitis and to evaluate the value of a comprehensive subjective evaluation (SGA) approach for the disease. Serum levels of white, globulin, transferrin, immunoglobulin, soluble interleukin-2 receptor (sIL-2R), C-reactive protein (CRP) and B were measured in 30 patients with ulcerative colitis and 30 healthy controls Factor level, at the same time with the SGA method for nutritional evaluation of patients. The results showed that patients with ulcerative colitis transfer plasma IgA, IgM was significantly lower than healthy people. SGA showed moderate malnutrition in 20 cases, severe malnutrition in 2 cases and normal nutrition in 8 cases. Conclusion: Most of patients with ulcerative colitis have malnutrition and immunodeficiency. The evaluation of nutritional status by SGA is consistent with the change of visceral protein and cellular immunity.