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本文利用正交实验设计,观察硒与维生素E对大鼠体内抗氧化能力的影响。实验结果表明,补充VE可显著提高大鼠血及组织中的VE含量,极明显地降低心、肝及血的脂质过氧化物(TBA)值,提高肝脏的硒含量。补充硒则可显著升高体内的GSH-Px活性,其中对肝脏GSH-Px活性的影响尤为明显,补硒还可增高心及血中的VE含量,降低肝及血中的TBA值。但补充硒及VE对超氧化物歧化酶(SOD)活性都无显著影响。就降低TBA值能力而言,补VE的效果明显优于补硒。
In this paper, the effect of selenium and vitamin E on antioxidant capacity in rats was observed by orthogonal design. The experimental results show that supplementation with VE can significantly increase the VE content in rat blood and tissues, significantly reduce the lipid peroxide (TBA) values in heart, liver and blood, and increase the selenium content in the liver. Supplementation of selenium can significantly increase the activity of GSH-Px in vivo, especially the effect on liver GSH-Px activity. Selenium supplementation can also increase the VE content in heart and blood, and decrease the TBA value in liver and blood. However, supplementation of selenium and VE had no significant effect on superoxide dismutase (SOD) activity. For the ability to reduce the TBA value, the effect of supplementing VE is significantly better than that of selenium supplementation.