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腺苷是一种强有力的血管扩张剂,其在扩冠中的“盗血”现象,造成正常与缺血心肌间血流分布上的差异,成为心肌显像探测心肌缺血的基础。大量文献证明,腺苷试验与运动和潘生丁试验心肌显像相比无明显差异,尤其适用于不能耐受运动试验者的冠心病检查。与潘生丁相比。其作用直接、迅速,体内半衰期短,扩冠效果确实,副作用轻微。采用14Omg/(kg.min)速度、6分钟静脉滴注腺苷,第三分钟注入核素行心肌显像方法,对冠心病诊断的灵敏度为83%~98%,特异性87%~100%.
Adenosine is a potent vasodilator and its “steal” phenomenon during crown expansion has caused a difference in the distribution of blood flow between normal and ischemic myocardium, which has become the basis of myocardial imaging in detection of myocardial ischemia. A large number of documents show that adenosine test and exercise and dipyridamole myocardial imaging was no significant difference, especially for those who can not tolerate exercise test coronary heart disease examination. Compared with dipyridamole. Its role is direct, rapid, short half-life in vivo, crown expansion effect is indeed minor side effects. Using 14Omg / (kg.min) speed, 6 minutes intravenous infusion of adenosine, the third minute injection of radionuclide myocardial imaging method for the diagnosis of coronary heart disease was 83% to 98%, the specificity of 87% to 100% .