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吡喹酮是一种广谱抗蠕虫药,对血吸虫、华支睾吸虫、肺吸虫及猪囊虫均有良好疗效。文献报告吡喹酮治疗日本血吸虫病25,693例,发生较严重反应者仅4.7％;治疗血吸虫病1,530例,出现严重反应仅0.6％,其中2例被迫中止治疗。最近我们用此药治疗3例脑囊虫病,两例出现严重反应,兹报告如下: 例1黄××,男,36岁,壮族,因反复头痛1年多,皮下发现多个结节4个多月,1983年5月11日入院。1982年2月开始出现发作性头痛,以颞顶部胀痛为主,常发生在清晨。4个月前发现皮下有多个可移动小结节,並感“复视”及行走不稳。否认大便排出缘虫节片史,有吃未熟猪肉习惯。体检:
Praziquantel is a broad-spectrum anthelmintic that has good efficacy against Schistosoma, Clonorchis sinensis, Paragonimus, and Cysticercosis. Reported in the literature praziquantel treatment of schistosomiasis japonica 25,693 cases, only 4.7% more serious reactions; treatment of schistosomiasis 1,530 cases, a serious reaction was only 0.6%, of which 2 were forced to suspend treatment. Recently we used this drug treatment of 3 cases of cysticercosis, two cases of serious reaction, it is reported as follows: Example 1 yellow × ×, male, 36 years old, Zhuang, repeated headache for more than 1 year, multiple subcutaneous nodules found more than 4 Month, May 11, 1983 admission. February 1982 onset of episodes of headache, pain in the top of the temporal-prone, often occurs in the early morning. 4 months ago found a number of subcutaneous can move nodules, and sense of “diplopia” and walking unsteady. Denied stool discharge edge bug film history, eat unhealthy pork habit. Physical examination: