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虽然试管内受精原先是为治疗女方的不育症,晚近亦包括用于男子治疗无效的精子减少症。在1983-84,75对夫妇进行过试管内受精;其中17例是男方有关或单纯是男方因素。全部精液均作了常规分析并进行精子穿透力鉴定(SPA Humster试验)。精子密度<20×10~6,活动度<60%或形态异常>40%,则考虑为男方因素病人。试管内受精采用标准的精子处理法,诱导排卵,吸出卵子与胚胎移植等标准方法。受精率在有男方因素的为57%,没有男方因素的为70%。受精率与精子的活动度或形态无关,却直接与精子密度相关。精子密度<10×10~6,10～20×10~6,与>20×10~6,其受精率分别为29%,44%与63%。
Although in vitro fertilization was originally used to treat the woman’s infertility, late-stage spermatozoa that are ineffective for men’s treatment are also included. In 1983-84, 75 couples underwent in vitro fertilization; 17 of them were men-related or simply men’s factors. All sperm were routinely analyzed and sperm penetration was assessed (SPA Humster test). Sperm density <20 × 10 ~ 6, activity <60% or morphological abnormalities> 40%, then consider the male factor patients. In vitro fertilization using standard methods of sperm handling, induction of ovulation, aspiration of eggs and embryo transfer and other standard methods. Fertility rates were 57% for men and 70% for men without men. Fertility and sperm motility or morphology has nothing to do, but directly related to sperm density. Sperm density <10 × 10 ~ 6,10 ~ 20 × 10 ~ 6, and> 20 × 10 ~ 6, the fertilization rates were 29%, 44% and 63% respectively.