论文部分内容阅读
测定51例乳腺癌,15例良性乳腺疾病及17例各种其它良、恶性疾病,结果显示:抗人乳腺癌单克隆抗体BG_6特异性较强,但诊断阳性率仅为76.7%,如与多克隆抗体CEA联合使用,可大大提高其阳性率,即两种抗体交叉阳性率可达96%.在乳腺癌类型中,恶性度较大的单纯癌、硬癌及浸润型导管癌,BG_6阳性率表达显著高于其它类型。对少数乳腺腺病及囊性增生症病例中出现阳性,可能反映乳腺上皮的癌变过程。
The determination of 51 cases of breast cancer, 15 cases of benign breast disease and 17 cases of various other benign and malignant diseases showed that the specificity of anti-human breast cancer monoclonal antibody BG 6 was strong, but the diagnostic positive rate was only 76.7%. Combined with polyclonal antibody CEA, it can greatly increase the positive rate, that is, the cross-positive rate of the two antibodies can reach 96%. Among the breast cancer types, the positive rate of BG_6 positive expression was significantly higher than that of other types in simple cancer, hard cancer, and infiltrating ductal cancer. Positive in a small number of cases of breast adenosis and cystic hyperplasia may reflect the cancerous process of breast epithelium.