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棉酚是一种有希望的男用避孕药。但因低血钾及不可逆性精子发生障碍,影响了该药的广泛使用。本文报道使用纯品醋酸棉酚及棉酚与氯化钾合并使用,考察醋酸棉酚低血钾及可逆性抗生育作用。应用成年、体重为15～18kg的雄性1angur猴为实验动物,分笼喂养。研究过程分三个周期,即给药前30天、给药期120天及恢复期105天。动物分三组,每组5只。A组为对照,仅供给赋形剂;B
Gossypol is a promising male contraceptive. However, due to hypokalemia and irreversible spermatogenesis disorders, affecting the widespread use of the drug. This article reports the use of pure gossypol acetate and gossypol and potassium chloride combined use of gossypol acetate hypokalemia and reversible anti-fertility. Male adult 1angur monkeys weighing 15 ~ 18kg were used as experimental animals and fed in cage. The research process is divided into three cycles, that is, 30 days before administration, 120 days of administration and 105 days of recovery. The animals were divided into three groups of five. Group A as a control, only excipients; B