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目的:观察呋麻滴鼻液联合地塞米松磷酸钠注射液滴鼻治疗驻戈壁官兵变应性鼻炎的临床疗效和安全性。方法:选择驻戈壁官兵变应性鼻炎188例,随机分为观察组104例和对照组84例。观察组给予呋麻滴鼻液联合地塞米松磷酸钠注射液滴鼻,对照组给予鼻炎康片口服。治疗后5天、10天复诊,比较两组疗效和不良反应发生情况。结果:治疗后5天,观察组总有效率53.8%,非常显著高于对照组的33.3%(P<0.01);治疗后10天,观察组总有效率88.5%,非常显著高于对照组的64.3%(P<0.01)。两组均未发生显著不良反应。结论:呋麻滴鼻液联合地塞米松磷酸钠注射液滴鼻局部治疗驻戈壁官兵变应性鼻炎,短期疗效好,且较安全。
Objective: To observe the clinical efficacy and safety of furosemide nasal drops combined with dexamethasone sodium phosphate injection nasal drops in the treatment of allergic rhinitis in Gobi soldiers. Methods: A total of 188 cases of allergic rhinitis in Gobi were randomly divided into observation group (n = 104) and control group (n = 84). Observation group was given furosemide nasal drops combined with dexamethasone sodium phosphate intranasally, the control group given rhinitis Kang Tablet oral. Five days after treatment, 10 days of referral, the two groups were compared efficacy and adverse reactions. Results: The total effective rate of observation group was 53.8% at 5 days after treatment, which was significantly higher than that of control group (33.3%, P <0.01). At 10 days after treatment, the total effective rate of observation group was 88.5%, significantly higher than that of control group 64.3% (P <0.01). No significant adverse reactions occurred in both groups. Conclusion: Nasal salviae miltiorrhizae combined with dexamethasone sodium phosphate injection intranasal local treatment of Gobal soldiers and soldiers in allergic rhinitis, short-term curative effect is good, and more secure.