１９９１年２～６月间江苏省徐州市辖邳县，发生１次中枢神经系统感染性疾病流行，病死率较高，发病者以学龄儿童为主，临床诊断为肠道病毒性脑膜炎。从１７例患者脑脊液、粪便等２３份标本中，分离出１８株相似病毒。该病毒为ＲＮＡ型，具有肠道病毒共有的理化特性和生物学性质，不被已知诊断血清中和，其抗血清也不能中和已知的肠道病毒。故可认为该病毒为一新型别的新型肠道病毒。血清流行病学调查表明，该病毒在毗邻疫区的未发病地区也曾广泛传播。 From February to June 1991, Xuzhou City, Jiangsu Province, Juxian County, there was a prevalence of central nervous system infections, the high mortality rate, the incidence of school-age children, clinical diagnosis of enteroviral meningitis. 18 strains of similar viruses were isolated from 23 samples of cerebrospinal fluid and feces of 17 patients. The virus is RNA type, with the common physical and chemical properties and biological properties of enterovirus, is not known to diagnose serum and its antisera can not neutralize known enterovirus. It can be considered a new type of new enterovirus. Serological epidemiological studies have shown that the virus has also been widely spread in areas not affected by the epidemic.