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对８２例输血后慢性丙型肝炎病人丙型肝炎病毒抗体（抗－ＨＣＶ）ＩｇＭ动态变化进行观察，８２例患者均检测到抗－ＨＣＶ抗体，其中５１例抗－ＨＣＶＩｇＭ阳性。抗－ＨＣＶＩｇＭ出现规律表现为４种类型：（１）持续检出型２４例（２９．２７％）；（２）间断检出型８例（９．７６％）；（３）短暂检出型１９例（２３．１７％）；（４）阴性型３１例（３７．８０％）。将８２例输血后慢性丙型肝炎抗－ＨＣＶＩｇＭ出现类型与丙氨酸转氨酶（ＡＬＴ）、ＨＣＶＲＮＡ消长情况比较，发现阴性型具有较低的ＡＬＴ峰值，而其它３型ＡＬＴ峰值较高（Ｐ＜０．０１）。８例经干扰素治疗的慢性活动性丙型肝炎患者，治疗前均有ＡＬＴ明显异常及ＨＣＶＲＮＡ、抗－ＨＣＶＩｇＭ阳性，治疗后１～３个月ＡＬＴ均转为正常，ＨＣＶＲＮＡ转为阴性，但其中只有３例伴抗－ＨＣＶＩｇＭ的阴转，随访１年发现，只有抗，ＨＣＶＩｇＭ阴转的３例病人得以痊愈，其余５例均在治疗后半年内病情复发。提示治疗中伴有抗－ＨＣＶＩｇＭ阴转的患者预后良好。
82 patients with chronic hepatitis C after transfusion of hepatitis C virus (anti-HCV) IgM dynamic changes were observed in 82 patients were detected anti-HCV antibodies, of which 51 were anti-HCVVI positive. There were four types of anti -HCVIgM: (1) 24 cases (29.27%) were detected continuously; (2) 8 cases (9.76%) were intermittent detected; (3) 19 cases (23.17%); (4) 31 cases of negative (37.80%). The comparison of the type of anti-HCVVIg in 82 chronic hepatitis C patients with that of alanine aminotransferase (ALT) and HCVRNA after transfusion showed that there was a lower ALT peak in the negative group and a higher peak in the other three ALTs (P <0 .01). 8 patients with chronic active hepatitis C treated by interferon had obvious abnormalities of ALT, HCVRNA and anti-HCVVI positive before treatment, ALT turned normal and HCVRNA turned negative one to three months after treatment, Only 3 cases with anti-HCVVIM negative conversion, found 1 year follow-up, only anti-HCVIgM negative conversion of 3 patients were cured, and the remaining 5 patients within 6 months after treatment, the disease recurrence. Prompt treatment with anti-HCVVI negative conversion of patients with good prognosis.