抗生素类药物已经被人们普遍接受,尽管长期使用此类药物对细菌的耐药选择性和耐药菌的泛滥有着不可推卸的责任。然而,抗生素的大量使用还不可否认地导致许多多重耐药菌的传染性和致病性增大,并且可能使医院获得性感染(HAIs)的病例数增加。因此,在遏制HAI发生的工作中应该更加关注对抗生素的管理。 Antibiotics have become widely accepted, although the long-term use of such drugs has an unshirkable responsibility for the drug resistance of bacteria and the proliferation of resistant bacteria. However, the extensive use of antibiotics has also undeniably led to an increase in the infectivity and pathogenicity of many multidrug-resistant bacteria and an increase in the number of cases of nosocomial infections (HAIs). Therefore, in the work to curb the occurrence of HAI should pay more attention to the management of antibiotics.