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我院收治一例自身免疫溶血性贫血(AIHA)患者,因长期服强的松、硫唑嘌呤而并发隐球菌脑膜炎、肺炎、咽喉炎等,实属罕见,现报道如下。男患,33岁,因发热、胸闷、腰痛、解酱油色尿,于1988年9月12日急诊入院。曾于1984年11月患者因头昏、心悸、气短、腰痛、解酱油色尿和皮肤黄染等首次住院诊治,当时检查Hb:30g/L,网织红细胞和间接胆红素明显增高,Coombs试验(+),骨髓红系显著增生,故确诊为“AIHA”,经用强的松、地塞米松、硫唑嘌呤等治疗病情好转出院。此后长期服强的松(40mg/日)和硫唑嘌呤(100mg/日)维持治疗,因患者自行加量或停服
In our hospital admitted to a case of autoimmune hemolytic anemia (AIHA) patients, due to long-term service prednisone, azathioprine and cryptococcal meningitis, pneumonia, laryngitis, etc., is rare, are reported below. Male suffering, 33 years old, due to fever, chest tightness, back pain, solution of soy sauce color urine, in September 12, 1988 emergency admission. Had in November 1984 patients with dizziness, palpitations, shortness of breath, back pain, solution of soy sauce and yellow skin yellow first inpatient treatment, check Hb: 30g / L, reticulocytes and indirect bilirubin was significantly higher, Coombs Test (+), bone marrow erythroid hyperplasia, it was diagnosed as “AIHA”, by prednisone, dexamethasone, azathioprine and other treatment improved condition was discharged. Since then long-term strong prednisone (40mg / day) and azathioprine (100mg / day) maintenance treatment, due to patients with their own dose or stop taking