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毛囊基质区细胞的迅速增殖使得毛发快速生长,鉴于这一快速增殖的细胞系统对于辐射非常敏感,同时又是唯一能够鉴别体表剂量分布的生物系统,有人提出毛囊作为一个有效的人类生物辐射剂量计的可能性.小鼠体表毛囊密度约为5000个/cm~2,其毛发生长周期很容易予以控制,如选择特定周龄的小鼠或通过拔取成熟的鼠毛使其生长同步化.新生的毛发为一细胞束,毛髓细胞排列成规则的柱状,其中的细胞总数即为髓细胞计数(MCC,从细胞束形成端至角化处).在完整新生的毛发、毛囊中,具有单列细胞的较小毛囊MCC平均含42.0±6.5个细胞,这一数值在一定时间内无明显变化,较大的毛囊则含有2～3列细胞,但其长度与较小的毛囊近乎相同或稍短一些.
The rapid proliferation of hair follicle stromal cells makes the hair grow rapidly. Given that the rapidly proliferating cell system is very sensitive to radiation and the only biological system capable of discriminating body surface dose distribution, it has been suggested that hair follicles act as an effective human biological radiation dose The mouse hair follicle density of about 5000 / cm ~ 2, the hair growth cycle can be easily controlled, such as the choice of a specific week-old mice or mice by pulling out the growth of mature hair synchronization. The newborn hair is a bundle of cells, and the myeloid cells are arranged in a regular columnar shape, and the total number of cells therein is the myelocytic count (MCC, from the end of the bundle formation to the keratosis). In intact nascent hair and hair follicles, The smaller hair follicle MCC of single-row cells contained an average of 42.0 ± 6.5 cells, with no significant change over time, whereas larger hair follicles contained 2-3 cells but were approximately the same length or length as the smaller hair follicles Shorter.