用沙门氏鼠伤寒杆菌 TM_(677)抗8-吖鸟嘌呤正向突变试验检测腊八豆、豆瓣酱、豆腐乳及虾酱的诱变性,均为阴性。模拟人胃情况进行亚硝化处理后,均显不同程度的诱变性,且呈明显的剂量-诱变性效应关系。所含诱变剂前体的种类较多。但制腊八豆的同种同批黄豆未显诱变性,说明诱变剂前体产生于霉制加工过程。如在亚硝化处理前,加 2800ppm的抗坏血酸,可抑制全部阳性效应。 The Salmonella typhimurium TM_ (677) anti-8- guanine guanine positive mutation test was used to detect the mutagenicity of Laba Bean, bean paste, fermented bean curd and shrimp paste, and all were negative. After mimicking the nitrosation of the human stomach, the mutagenicity was different in different degrees, and there was a clear dose-mutagenicity relationship. There are many types of mutagen precursors contained. However, the homozygous soybeans of Laba soya bean did not show obvious mutagenicity, indicating that mutagen precursors were produced during mildew processing. For example, adding 2800 ppm of ascorbic acid before nitrosation can inhibit all positive effects.