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本文调查了182例鼻咽癌病例及其对照者一、二级亲属成员的家族癌曾患情况,结果表明鼻咽癌家族聚集性十分明显,鼻咽癌病例一级亲属成员易患鼻咽癌的风险为正常人群的13.2倍。鼻咽癌的遗传方式较为符合多基因遗传,遗传度为49±6%。
This paper investigated the family cancer prevalence of 182 nasopharyngeal carcinoma cases and their controls, first- and second-degree relatives. The results showed that the family clustering of nasopharyngeal carcinoma is very obvious. The first-degree relatives of nasopharyngeal carcinoma patients are prone to nasopharyngeal carcinoma. The risk is 13.2 times that of the normal population. The genetic pattern of nasopharyngeal carcinoma is more consistent with polygenic inheritance, with a heritability of 49±6%.