论文部分内容阅读
近年来由于诊断技术的不断发展和新造影剂的问世,尿路造影剂的应用日益增多,它不仅应用于尿路造影,还用于血管造影,剂量也逐渐增大。但由此而带来的肾毒性问题再次引起人们的关注。在肾毒性急性肾衰的病因中,造影剂所致者仅次于氨基甙类抗生素居第二位。如Mc Murray等报告1967～1975年间造影剂所致的急性肾衰占16％,而Galpin等报告1976～1977年间已升高至29%。Swartz以造影后血肌酐增加1mg/dl为诊断标准,发现肾功能损害者达12％,因此对造影剂的肾毒性问题加以复习有助于预防此并发症。一、尿路造影剂的特点 50年代以后,尿路造影
In recent years, due to the continuous development of diagnostic techniques and the advent of new contrast agents, the application of urinary contrast media is increasing. It is not only used in urography, but also used in angiography, and the dosage is gradually increased. However, the nephrotoxicity brought about by this once again aroused people’s attention. In the etiology of acute renal failure with nephrotoxicity, contrast agents are second only to aminoglycosides. For example, Mc Murray et al. Reported 16% of acute renal failure caused by contrast medium between 1967 and 1975, while Galpin et al. Reported an increase of 29% between 1976 and 1977. Swartz to post-contrast serum creatinine increase 1mg / dl as the diagnostic criteria and found that 12% of renal dysfunction, so the nephrotoxicity of contrast agents to review the problem will help prevent this complication. First, the characteristics of urinary tract contrast agents 50 years later, urography