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目的:探讨肝硬化患者营养不良的相关因素。方法:已确诊49例肝硬化住院患者空腹测血常规、血生化、肝纤维化、血凝分析、微量元素测定、尿常规,及人体测量学指标:身高、体重(weight)、上臂围(Mid-upperarmcir cumference,AC)、上臂肌围(Mid-upper arm muscle circumference,AMC)、肱三头肌皮褶厚度(Triceps skin fold thickness,TSF)、髂骨上皮褶厚度(Ilium skin fold thickness,ISF)、腓肠肌围((Gastrocnemius muscle circumference,GC),计算体重指数(Body mass index,BMI)、Pignete指数、比胸围(Ratio of Chest circumference and body Height,C/H)、Rohrer指数、Vervaeck指数等指标110项,采用主观全面营养评价法(Subjective global assessment,SGA)进行营养评估。结果:计量资料应用t检验、计数资料应用X2检验进行单因素分析,筛选出与肝硬化营养不良有关的因素26项,纳入Logistic回归向前逐步选择法(似然比)行多因素分析,GC、AC、ISF、阴离子间隙(AG)4项指标的降低与肝硬化患者营养不良的发生有关系。结论:在采用SGA法评估肝硬化患者营养状况时,应注意GC、AC、ISF及AG的变化。
Objective: To investigate the related factors of malnutrition in patients with cirrhosis. Methods: Fasting blood tests, blood biochemistry, liver fibrosis, hemagglutination, trace elements determination, urinalysis, and anthropometry were performed in 49 patients with cirrhosis hospitalized. Height, weight, Mid (AC), mid-upper arm muscle circumference (AMC), triceps skin fold thickness (TSF), ilium skin fold thickness (ISF) Gastrocnemius muscle circumference (GC), Body mass index (BMI), Pignete index, Ratio of Chest circumference and body height (C / H), Rohrer index and Vervaeck index Term subjective global assessment (SGA) for nutritional assessment.Results: The measurement data using t test, count data using the X2 test univariate analysis, screened out with the liver cirrhosis of the 26 factors related to malnutrition, Multivariate analysis was included in the Logistic regression forward selection method (Likelihood ratio). Four indicators of GC, AC, ISF and anion gap (AG) were decreased in patients with cirrhosis There is a relationship Conclusion: When using SGA method to assess the nutritional status of patients with cirrhosis, should pay attention to changes GC, AC, ISF and AG.