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作者用马桑内酯3.8μl(19μg)注射于成年大鼠皮质内运动区,成功地造成大鼠急性局灶运动型癫痫模型。此模型在国内外尚未见报道,为探讨癫痫的发病机理提供了一个新模型。其制作方法简便,用药量少,易于重复。
The authors injected 3.8 μl (19 μg) of coriaria lactone into the cortical motor area of adult rats to successfully create an acute focal motor epilepsy model in rats. This model has not been reported at home and abroad, providing a new model for the study of the pathogenesis of epilepsy. The production method is simple, the dosage is small, and it is easy to repeat.