脂质体是一类具有类似生物膜结构的双层分子小囊,具有与生物膜相类似的结构和特性。有关脂质体作为药物载体的研究,一直是脂质体研究的重点,并在脂质体的组成、粒径分布、稳定性、药代动力学、药效学等多方面取得了进展。现已有二个抗肿瘤药物和三个抗真菌药物的脂质体剂型被批准用于临床。 Liposomes are a series of double-layered molecular vesicles with biofilm-like structure with similar structure and characteristics to biofilms. Studies on liposomes as drug carriers have been the focus of liposome research, and have made progress in the aspects of liposome composition, particle size distribution, stability, pharmacokinetics and pharmacodynamics. Two antitumor drugs and three antifungal liposomal formulations are now approved for clinical use.