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目的:观察防疤烧伤膏对大鼠创面修复的影响。方法:采用大鼠皮肤切割伤模型,创面外用防疤烧伤膏,并采用碱性成纤维细胞生长因子(basic fibroblast growth factor,bFGF)和空白处理作为阳性和阴性对照。透明膜标记称量法和注水法记录伤后3、7、14d 创面面积和伤腔容积,伤后7、14d 取创面组织作组织学检查。结果:防疤烧伤膏能够减轻伤口炎症反应,促进坏死组织脱落,缩短伤口愈合时间。结论:外用防疤烧伤膏对创面修复有促进作用。
OBJECTIVE: To observe the effect of Zhiqi burn cream on the wound repair in rats. METHODS: Rat skin wound injury model was used. The topical topical topical burn cream was treated with basic fibroblast growth factor (bFGF) and blank treatment as positive and negative controls. The area of the wound and wound cavity volume were recorded on the 3rd, 7th, and 14th day after wound injury by the transparent film labeling method and water injection method. The wound tissue was taken at 7 and 14 days after injury for histological examination. Results: Anti-caries burn ointment can reduce the inflammatory reaction of wound, promote the shedding of necrotic tissue and shorten the wound healing time. Conclusion: The external use of moth-occluded burn cream can promote wound repair.