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哮喘是一种以慢性气道炎症为特征的变态反应性疾病。吸入糖皮质激素(GC)具有抑制气道炎症、缓解哮喘症状的功能,已成为防治哮喘的第一线药物。长期吸入GC是否会产生与全身用药类似的副作用已引起医患双方的极大关注。本文着重阐述吸入GC对哮喘儿童的骨代谢和生长发育的影响。
Asthma is an allergic disease characterized by chronic airway inflammation. Inhaled glucocorticoid (GC) has the function of inhibiting airway inflammation and alleviating the symptoms of asthma and has become the first line of medicine for the prevention and treatment of asthma. Long-term inhalation of GC will produce similar side effects with systemic medication has caused great concern to both doctors and patients. This article highlights the effects of inhaled GC on bone metabolism and growth in asthmatic children.